2CW6
Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Hydroxymethylglutaryl-CoA lyase, mitochondrial | polymer | 298 | 31577.6 | 6 | UniProt (P35914) Pfam (PF00682) In PDB | Homo sapiens (human) | HMG-CoA lyase, HL, 3-hydroxy-3-methylglutarate-CoA lyase |
| 2 | A, B, C, D, E... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 3 | A | 3-HYDROXYPENTANEDIOIC ACID | non-polymer | 148.1 | 1 | Chemie (3HG) | |||
| 4 | water | water | 18.0 | 565 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 189465.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 293.9 | |
| All* | Total formula weight | 189759.7 |
