2CPU
SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALPHA-AMYLASE | polymer | 496 | 55930.3 | 1 | UniProt (P04746) Pfam (PF00128) Pfam (PF02806) | Homo sapiens (human) | |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 1 - 496 (UniProt: P04746)
| PDB | External Database | Details |
|---|---|---|
| Asn 300 | Glu | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55930.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 75.5 | |
| All* | Total formula weight | 56005.9 |
