2COI
Crystal structure of oxidized human cytosolic branched-chain aminotransferase complexed with gabapentin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | branched chain aminotransferase 1, cytosolic | polymer | 386 | 43079.1 | 2 | UniProt (P54687) Pfam (PF01063) | Homo sapiens (human) | |
| 2 | C, F (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D, G (A, B) | [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID | non-polymer | 171.2 | 2 | Chemie (GBN) | |||
| 4 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 580 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 386 (UniProt: P54687)
| PDB | External Database | Details |
|---|---|---|
| Arg 379 | Ser 379 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86158.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 861.1 | |
| All* | Total formula weight | 87019.3 |
