2CNL
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CASPASE-3 SUBUNIT P17 | polymer | 147 | 16639.9 | 1 | UniProt (P42574) Pfam (PF00656) | HOMO SAPIENS (HUMAN) | CASP-3, APOPAIN, CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP- 32, SREBP CLEAVAGE ACTIVITY 1, SCA-1 |
| 2 | B (B) | CASPASE-3 SUBUNIT P12 | polymer | 103 | 11981.7 | 1 | UniProt (P42574) Pfam (PF00656) | HOMO SAPIENS (HUMAN) | CASP-3, APOPAIN, CYSTEINE PROTEASE CPP32, YAMA PROTEIN, CPP- 32, SREBP CLEAVAGE ACTIVITY 1, SCA-1 |
| 3 | C (I) | AZA-PEPTIDE EPOXIDE | polymer | 5 | 791.2 | 1 | BIRD (PRD_000672) | SYNTHETIC CONSTRUCT | |
| 4 | D, E, F (A, B, I) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29412.8 | |
| All* | Total formula weight | 29412.8 |
