2CMC
Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | polymer | 304 | 35549.4 | 1 | UniProt (P18031) Pfam (PF00102) | HOMO SAPIENS (HUMAN) | PROTEIN TYROSINE PHOSPHATASE 1B |
| 2 | B (A) | N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE | non-polymer | 483.4 | 1 | Chemie (DFM) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 5 | E (A) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35549.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 871.8 | |
| All* | Total formula weight | 36421.3 |
