2CM7
Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | polymer | 321 | 37365.6 | 1 | UniProt (P18031) Pfam (PF00102) | HOMO SAPIENS (HUMAN) | PROTEIN TYROSINE PHOSPHATASE 1B, PTP-1B |
| 2 | B (A) | ISOTHIAZOLIDINONE ANALOG | non-polymer | 486.5 | 1 | Chemie (IZD) | |||
| 3 | C (A) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37365.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 486.5 | |
| All* | Total formula weight | 37852.2 |
