2CLX
4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE |
2 | A | 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL | non-polymer | 218.2 | 1 | Chemie (F18) | |||
3 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33976.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 218.2 | |
All* | Total formula weight | 34194.7 |