2CLQ
Structure of mitogen-activated protein kinase kinase kinase 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 | polymer | 295 | 33197.9 | 2 | UniProt (Q99683) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | MAP3K5, MAPK/ERK KINASE KINASE 5, MEK KINASE 5, MEKK 5, APOPTOSIS SIGNAL-REGULATING KINASE 1, ASK-1 |
| 2 | C, D (A, B) | STAUROSPORINE | non-polymer | 466.5 | 2 | Chemie (STU) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B: 659 - 951 (UniProt: Q99683)
| PDB | External Database | Details |
|---|---|---|
| Ser 657 | - | expression tag |
| Met 658 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66395.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 933.1 | |
| All* | Total formula weight | 67328.8 |
