2CLQ
Structure of mitogen-activated protein kinase kinase kinase 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 | polymer | 295 | 33197.9 | 2 | UniProt (Q99683) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | MAP3K5, MAPK/ERK KINASE KINASE 5, MEK KINASE 5, MEKK 5, APOPTOSIS SIGNAL-REGULATING KINASE 1, ASK-1 |
| 2 | C, D (A, B) | STAUROSPORINE | non-polymer | 466.5 | 2 | Chemie (STU) PubChem (71203703) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (42610657) PubChem (44299148) PubChem (358479) PubChem (49831000) PubChem (5280487) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (12046017) PubChem (68262703) PubChem (68306294) PubChem (73953205) PubChem (86306248) PubChem (122130844) PubChem (5279) PubChem (44259) PubChem (451705) PubChem (5459111) PubChem (6419748) PubChem (9804568) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B: 659 - 951 (UniProt: Q99683)
| PDB | External Database | Details |
|---|---|---|
| Ser 657 | - | expression tag |
| Met 658 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66395.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 933.1 | |
| All* | Total formula weight | 67328.8 |
