2CL7
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | GTPASE HRAS | polymer | 166 | 18799.1 | 1 | UniProt (P01112) Pfam (PF00071) | HOMO SAPIENS (HUMAN) | H-RAS P21, TRANSFORMING PROTEIN P21, P21RAS, H-RAS-1, C-H-RAS |
| 2 | B, C (X) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D (X) | N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE | non-polymer | 293.3 | 1 | Chemie (XY2) PubChem (6857727) | |||
| 4 | E (X) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | F (X) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence modifications
X: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Cys 32 | Tyr 32 | engineered mutation |
| Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18799.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 865.1 | |
| All* | Total formula weight | 19664.2 |
