2CKE
Human death-associated DRP-1 kinase in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | DEATH-ASSOCIATED PROTEIN KINASE 2 | polymer | 321 | 37166.5 | 4 | UniProt (Q9UIK4) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | HUMAN DRP-1 KINASE, DAP KINASE 2, DAP-KINASE- RELATED PROTEIN 1, DRP-1 |
| 2 | A, B, C, D | N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE | non-polymer | 251.3 | 4 | Chemie (IQU) | |||
| 3 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 320 (UniProt: Q9UIK4)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 231 | Ala 241 | conflict |
| His 243 | Gln 253 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 148666.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1005.2 | |
| All* | Total formula weight | 149671.2 |
