2CIO
The high resolution x-ray structure of papain complexed with fragments of the Trypanosoma brucei cysteine protease inhibitor ICP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PAPAIN | polymer | 212 | 23499.3 | 1 | UniProt (P00784) Pfam (PF00112) | CARICA PAPAYA | PAPAYA PROTEINASE I, PPI, ALLERGEN, CARP1PAPAIN |
| 2 | B (B) | INHIBITOR OF CYSTEINE PEPTIDASE | polymer | 121 | 13449.2 | 1 | UniProt (Q868H0) Pfam (PF09394) | TRYPANOSOMA BRUCEI | CYSTEINE PROTEASE INHIBITOR, ICP |
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A: 1 - 212 (UniProt: P00784)
| PDB | External Database | Details |
|---|---|---|
| Gln 47 | Glu 180 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36948.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 361.3 | |
| All* | Total formula weight | 37309.8 |
