2CHZ
A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-93
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | polymer | 966 | 110756.2 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | HOMO SAPIENS (HUMAN) | PHOSPHOINOSITIDE 3-KINASE, PI3-KINASE P110 SUBUNIT GAMMA, PTDINS-3-KINASE P110, PI3K, PI3KGAMMA |
2 | A | N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE | non-polymer | 389.9 | 1 | Chemie (093) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 110756.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 389.9 | |
All* | Total formula weight | 111146.0 |