2CHZ

A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-93

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM	polymer	966	110756.2	1	UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454)	HOMO SAPIENS (HUMAN)	PHOSPHOINOSITIDE 3-KINASE, PI3-KINASE P110 SUBUNIT GAMMA, PTDINS-3-KINASE P110, PI3K, PI3KGAMMA
2	B (A)	N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE	non-polymer		389.9	1	Chemie (093)

Sequence modifications

A: 143 - 143 (PDB: 2CHZ)
A: 1103 - 1108 (PDB: 2CHZ)
A: 144 - 1102 (UniProt: P48736)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	110756.2
Non-Polymers*	Number of molecules	1
	Total formula weight	389.9
All*	Total formula weight	111146.0

*Water molecules are not included.