2CHX
A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-90
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | polymer | 966 | 110756.2 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | HOMO SAPIENS (HUMAN) | PHOSPHOINOSITIDE 3-KINASE, PI3-KINASE P110 SUBUNIT GAMMA, PTDINS-3-KINASE P110, PI3K, PI3KGAMMA |
| 2 | A | N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE | non-polymer | 350.4 | 1 | Chemie (090) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 110756.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 350.4 | |
| All* | Total formula weight | 111106.5 |
