2CGR
LOCAL AND TRANSMITTED CONFORMATIONAL CHANGES ON COMPLEXATION OF AN ANTI-SWEETENER FAB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | IGG2B-KAPPA NC6.8 FAB (LIGHT CHAIN) | polymer | 219 | 24123.8 | 1 | PIR (S16112) Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (A2P1G9) | Mus musculus (house mouse) | |
| 2 | B (H) | IGG2B-KAPPA NC6.8 FAB (HEAVY CHAIN) | polymer | 214 | 22903.5 | 1 | GenBank (1613777) | Mus musculus (house mouse) | |
| 3 | C (H) | N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID | non-polymer | 384.4 | 1 | Chemie (GAS) | |||
| 4 | D, E (L, H) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
L: 3 - 219 (PIR: S16112)
H: 2 - 214 (GenBank: 1613777)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Thr 7 | CONFLICT |
| Pro 25 | Ser 25 | CONFLICT |
| His 39 | Tyr 39 | CONFLICT |
| Leu 51 | Pro 51 | CONFLICT |
| Ala 75 | Asp 75 | CONFLICT |
| Ser 94 | Phe 94 | CONFLICT |
| Lys 108 | Arg 108 | CONFLICT |
| Leu 111 | Ile 111 | CONFLICT |
| PDB | External Database | Details |
|---|---|---|
| Leu 5 | Val 5 | CONFLICT |
| Gln 19 | Lys 19 | CONFLICT |
| Glu 31 | Ser 31 | CONFLICT |
| Val 37 | Ile 37 | CONFLICT |
| Glu 39 | Gln 39 | CONFLICT |
| Ile 48 | Thr 48 | CONFLICT |
| Arg 57 | Thr 57 | CONFLICT |
| Asn 59 | Lys 59 | CONFLICT |
| Arg 61 | Asn 61 | CONFLICT |
| Gly 66 | Asp 66 | CONFLICT |
| Thr 97 | Ala 97 | CONFLICT |
| - | Ser 99 | DELETION |
| - | Tyr 100 | DELETION |
| Gly 99 | Arg 101 | CONFLICT |
| Ser 101 | Ala 103 | CONFLICT |
| Ser 102 | Pro 104 | CONFLICT |
| Ala 116 | Ser 118 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47027.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 47411.7 |
