2CD2
LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DIHYDROFOLATE REDUCTASE | polymer | 206 | 23918.5 | 1 | UniProt (P16184) Pfam (PF00186) | Pneumocystis carinii | PCDHFR |
2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
3 | C (A) | FOLIC ACID | non-polymer | 441.4 | 1 | Chemie (FOL) | |||
4 | D (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23918.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1184.8 | |
All* | Total formula weight | 25103.3 |