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2CD2

LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer20623918.51UniProt (P16184)
Pfam (PF00186)
Pneumocystis cariniiPCDHFR
2B
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3C
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
4D
(A)
waterwater18.075Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23918.5
Non-Polymers*Number of molecules2
Total formula weight1184.8
All*Total formula weight25103.3
*Water molecules are not included.

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