2CCH

The crystal structure of CDK2 cyclin A in complex with a substrate peptide derived from CDC modified with a gamma-linked ATP analogue

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	CELL DIVISION PROTEIN KINASE 2	polymer	299	34143.5	2	UniProt (P24941) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE
2	B, D (B, D)	CYCLIN A2	polymer	260	29867.5	2	UniProt (P20248) Pfam (PF00134) Pfam (PF02984)	HOMO SAPIENS (HUMAN)	CYCLIN-A
3	E, F (E, F)	CELL DIVISION CONTROL PROTEIN 6 HOMOLOG	polymer	12	1459.7	2	UniProt (Q99741)	HOMO SAPIENS	CDC6-BIS, CDC6-RELATED PROTEIN, P62, CDC6, HSCDC6, HSCDC18
4	G, K (A, C)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	H (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	I, J (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	L, M, N, O, P... (A, B, C, D, E...)	water	water		18.0	1045	Chemie (HOH)

Sequence modifications

A, C: 0 - 0 (PDB: 2CCH)
A, C: 1 - 298 (UniProt: P24941)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	130941.5
Non-Polymers*	Number of molecules	5
	Total formula weight	1294.6
All*	Total formula weight	132236.1

*Water molecules are not included.