2CBT
Crystal structure of the neocarzinostatin 4Tes1 mutant bound testosterone hemisuccinate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NEOCARZINOSTATIN | polymer | 112 | 11290.3 | 2 | UniProt (P0A3R9) | STREPTOMYCES CARZINOSTATICUS | NCS, MITOMALCIN, MMC |
| 2 | C, D (A, B) | TESTOSTERONE HEMISUCCINATE | non-polymer | 388.5 | 2 | Chemie (TH2) PubChem (124867314) PubChem (119202) PubChem (248933) PubChem (580175) PubChem (1761053) PubChem (124898307) PubChem (7076010) PubChem (11872512) PubChem (11872514) PubChem (16395642) PubChem (57367994) PubChem (166888263) PubChem (11872510) PubChem (21119834) PubChem (99568890) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 1001 - 1112 (UniProt: P0A3R9)
| PDB | External Database | Details |
|---|---|---|
| Trp 1033 | Asp 67 | engineered mutation |
| Ala 1035 | Gly 69 | engineered mutation |
| Ser 1037 | Cys 71 | engineered mutation |
| Tyr 1045 | Leu 79 | engineered mutation |
| Ser 1047 | Cys 81 | engineered mutation |
| Ile 1052 | Phe 86 | engineered mutation |
| Trp 1078 | Phe 112 | engineered mutation |
| His 1094 | Gln 128 | engineered mutation |
| Thr 1096 | Gly 130 | engineered mutation |
| Arg 1098 | Ser 132 | engineered mutation |
| Leu 1101 | Ala 135 | engineered mutation |
| Ser 1102 | Gly 136 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22580.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 777.0 | |
| All* | Total formula weight | 23357.6 |
