2C72
Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | AMINE OXIDASE (FLAVIN-CONTAINING) B | polymer | 520 | 58812.7 | 2 | UniProt (P27338) Pfam (PF01593) In PDB | HOMO SAPIENS (HUMAN) | MONOAMINE OXIDASE B, MAO-B |
2 | A, B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
3 | A, B | N-PROPARGYL-1(S)-AMINOINDAN | non-polymer | 171.2 | 2 | Chemie (RSA) | |||
4 | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1 (PDB: 2C72)
A, B: 2 - 520 (UniProt: P27338)
A, B: 2 - 520 (UniProt: P27338)
PDB | External Database | Details |
---|---|---|
His 435 | Tyr 434 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 117625.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1913.6 | |
All* | Total formula weight | 119539.0 |