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2C70

Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
AMINE OXIDASE (FLAVIN-CONTAINING) Bpolymer52058837.72UniProt (P27338)
Pfam (PF01593)
HOMO SAPIENS (HUMAN)MONOAMINE OXIDASE B, MAO-B
2C, E
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
3D, F
(A, B)
P-NITRO-BENZYLAMINEnon-polymer152.22Chemie (PNZ)
4G, H
(A, B)
waterwater18.0529Chemie (HOH)
Sequence modifications
A, B: 1 - 1 (PDB: 2C70)
A, B: 2 - 520 (UniProt: P27338)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight117675.5
Non-Polymers*Number of molecules4
Total formula weight1875.4
All*Total formula weight119550.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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