2C6T

Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	CELL DIVISION PROTEIN KINASE 2	polymer	298	34056.5	2	UniProt (P24941) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	P33 PROTEIN KINASE
2	B, D (B, D)	CYCLIN A2	polymer	258	29624.3	2	UniProt (P20248) Pfam (PF00134) Pfam (PF02984)	HOMO SAPIENS (HUMAN)	CYCLIN-A
3	E, F (A, C)	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	non-polymer		388.4	2	Chemie (DT5)
4	G, H, I, J (A, B, C, D)	water	water		18.0	357	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	127361.5
Non-Polymers*	Number of molecules	2
	Total formula weight	776.9
All*	Total formula weight	128138.4

*Water molecules are not included.