2C53
A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | URACIL DNA GLYCOSYLASE | polymer | 244 | 27341.4 | 1 | UniProt (P10186) Pfam (PF03167) In PDB | HUMAN HERPESVIRUS 1 | |
| 2 | A | 2'-DEOXYURIDINE | non-polymer | 228.2 | 1 | Chemie (DUR) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 1 - 244 (UniProt: P10186)
| PDB | External Database | Details |
|---|---|---|
| Asn 88 | Asp 178 | engineered mutation |
| Asn 210 | His 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27341.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 596.6 | |
| All* | Total formula weight | 27938.0 |
