2C53
A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | URACIL DNA GLYCOSYLASE | polymer | 244 | 27341.4 | 1 | UniProt (P10186) Pfam (PF03167) | HUMAN HERPESVIRUS 1 | |
| 2 | B (A) | 2'-DEOXYURIDINE | non-polymer | 228.2 | 1 | Chemie (DUR) PubChem (640) PubChem (13712) PubChem (43834318) PubChem (22298594) PubChem (57089381) PubChem (67797426) PubChem (453556) PubChem (644272) PubChem (687971) PubChem (1263358) PubChem (91286369) PubChem (6925687) PubChem (6541352) PubChem (6618794) PubChem (7059422) PubChem (13048618) PubChem (142182554) PubChem (142978971) | |||
| 3 | C, D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 4 | G (A) | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 1 - 244 (UniProt: P10186)
| PDB | External Database | Details |
|---|---|---|
| Asn 88 | Asp 178 | engineered mutation |
| Asn 210 | His 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27341.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 596.6 | |
| All* | Total formula weight | 27938.0 |
