2C2K
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CASPASE-3 SUBUNIT P17 | polymer | 147 | 16639.9 | 1 | UniProt (P42574) Pfam (PF00656) | HOMO SAPIENS (HUMAN) | |
| 2 | B (B) | CASPASE-3 SUBUNIT P12 | polymer | 103 | 11981.7 | 1 | UniProt (P42574) Pfam (PF00656) | HOMO SAPIENS (HUMAN) | |
| 3 | C (C) | AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID | polymer | 5 | 714.1 | 1 | BIRD (PRD_000330) | SYNTHETIC CONSTRUCT | |
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29335.7 | |
| All* | Total formula weight | 29335.7 |
