2C1B
Structure of cAMP-dependent protein kinase complexed with (4R,2S)-5'-(4-(4-Chlorobenzyloxy)pyrrolidin-2-ylmethanesulfonyl)isoquinoline
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CAMP-DEPENDENT PROTEIN KINASE | polymer | 351 | 40837.6 | 1 | UniProt (P00517) Pfam (PF00069) In PDB | BOS TAURUS | PROTEIN KINASE A, ALPHA-CATALYTIC SUBUNIT, PKA C-ALPHA |
2 | I | CAMP-DEPENDENT PROTEIN KINASE INHIBITOR | polymer | 20 | 2226.4 | 1 | UniProt (P61925) In PDB | HOMO SAPIENS | ALPHA FORM, PKI-ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN ISOFORM |
3 | A | (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE | non-polymer | 431.9 | 1 | Chemie (CQP) | |||
4 | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43064.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 431.9 | |
All* | Total formula weight | 43496.0 |