2C1A

Structure of cAMP-dependent protein kinase complexed with Isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino) ethyl)amide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CAMP-DEPENDENT PROTEIN KINASE	polymer	351	40837.6	1	UniProt (P00517) Pfam (PF00069) In PDB	BOS TAURUS	PROTEIN KINASE A, ALPHA-CATALYTIC SUBUNIT, PKA C-ALPHA
2	I	CAMP-DEPENDENT PROTEIN KINASE INHIBITOR	polymer	20	2226.4	1	UniProt (P61925) In PDB	HOMO SAPIENS	ALPHA FORM, PKI-ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN ISOFORM
3	A	ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE	non-polymer		419.9	1	Chemie (I5S)
4		water	water		18.0	415	Chemie (HOH)

Sequence modifications

A: 0 - 0 (PDB: 2C1A)
A: 1 - 350 (UniProt: P00517)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43064.0
Non-Polymers*	Number of molecules	1
	Total formula weight	419.9
All*	Total formula weight	43483.9

*Water molecules are not included.