2BZS
Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NRH DEHYDROGENASE [QUINONE] 2 | polymer | 236 | 26460.0 | 2 | UniProt (P16083) Pfam (PF02525) In PDB | HOMO SAPIENS (HUMAN) | NRH QUINONE OXIDO-REDUCTASE TYPE 2, QUINONE REDUCTASE 2, QR2, NRH QUINONE OXIDOREDUCTASE 2 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
4 | A, B | 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE | non-polymer | 252.2 | 2 | Chemie (CB1) | |||
5 | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52920.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2206.3 | |
All* | Total formula weight | 55126.4 |