2BZH
CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1 | polymer | 313 | 35632.6 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | |
| 2 | B | RUTHENIUM-PYRIDOCARBAZOLE-1 | non-polymer | 480.4 | 1 | Chemie (HB1) | |||
| 3 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
B: 1 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | Arg 250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35632.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 578.0 | |
| All* | Total formula weight | 36210.6 |
