2BYI
3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HEAT SHOCK PROTEIN HSP90-ALPHA | polymer | 235 | 26470.6 | 1 | UniProt (P07900) Pfam (PF13589) | HOMO SAPIENS (HUMAN) | HSP 86 |
| 2 | B (A) | 3-(5-CHLORO-2,4-DIHYDROXY-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 4-SULFAMOYL-BENZYLAMIDE | non-polymer | 422.8 | 1 | Chemie (2DD) | |||
| 3 | C (A) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26470.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 422.8 | |
| All* | Total formula weight | 26893.4 |
