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2BYH

3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHEAT SHOCK PROTEIN HSP90-ALPHApolymer23526470.61UniProt (P07900)
Pfam (PF13589)
In PDB
HOMO SAPIENS (HUMAN)HSP 86
2AN-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDEnon-polymer371.81Chemie (2D7)
3waterwater18.0246Chemie (HOH)
Sequence modifications
A: 2 - 10 (PDB: 2BYH)
A: 11 - 236 (UniProt: P07900)
PDBExternal DatabaseDetails
Ser 63Thr 62conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26470.6
Non-Polymers*Number of molecules1
Total formula weight371.8
All*Total formula weight26842.4
*Water molecules are not included.

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PDB entries from 2024-04-24

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