2BXV
Dual binding mode of a novel series of DHODH inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DIHYDROOROTATE DEHYDROGENASE | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | HOMO SAPIENS (Human) | DIHYDROOROTATE OXIDASE, DHODEHASE |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 5 | E (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 6 | F (A) | 2-({[3-FLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID | non-polymer | 409.3 | 1 | Chemie (3FT) | |||
| 7 | G (A) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1176.9 | |
| All* | Total formula weight | 41033.4 |
