2BIO
human p53 core domain mutant M133L-V203A-N239Y-R249S-N268D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CELLULAR TUMOR ANTIGEN P53 | polymer | 219 | 24520.7 | 1 | UniProt (P04637) Pfam (PF00870) | HOMO SAPIENS (HUMAN) | TUMOUR SUPPRESSOR P53, PHOSPHOPROTEIN P53, ANTIGEN NY-CO-13 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 94 - 312 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Leu 133 | Met 133 | engineered mutation |
| Ala 203 | Val 203 | engineered mutation |
| Tyr 239 | Asn 239 | engineered mutation |
| Ser 249 | Arg 249 | engineered mutation |
| Asp 268 | Asn 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24520.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 24586.1 |
