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2BFM

Leishmania major pteridine reductase 1 in complex with NADP and trimethoprim

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
PTERIDINE REDUCTASE 1polymer28830440.64UniProt (Q01782)
Pfam (PF13561)
LEISHMANIA MAJORH REGION METHOTREXATE RESISTANCE PROTEIN
2E, G, I, J
(A, B, C, D)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.44Chemie (NDP)
3F, H
(A, B)
TRIMETHOPRIMnon-polymer290.32Chemie (TOP)
4K, L, M, N
(A, B, C, D)
waterwater18.0185Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight121762.3
Non-Polymers*Number of molecules6
Total formula weight3562.3
All*Total formula weight125324.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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