2BEL
Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1 | polymer | 283 | 31106.0 | 4 | UniProt (P28845) Pfam (PF00106) In PDB | HOMO SAPIENS (HUMAN) | HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1,11-DH, 11-BETA-HSD1 |
2 | A, B, C, D | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
3 | A, B, C, D | CARBENOXOLONE | non-polymer | 570.8 | 4 | Chemie (CBO) | |||
4 | A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
5 | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 25 (PDB: 2BEL)
A, B, C, D: 285 - 286 (PDB: 2BEL)
A, B, C, D: 26 - 284 (UniProt: P28845)
A, B, C, D: 285 - 286 (PDB: 2BEL)
A, B, C, D: 26 - 284 (UniProt: P28845)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 124423.9 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 5398.5 | |
All* | Total formula weight | 129822.3 |