2BED
Structure of FPT bound to inhibitor SCH207736
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit | polymer | 313 | 37691.3 | 1 | UniProt (Q04631) Pfam (PF01239) In PDB | Rattus norvegicus (Norway rat) | CAAX farnesyltransferase alpha subunit, Ras proteins prenyltransferase alpha, FTase-alpha, Type I protein geranyl-geranyltransferase alpha subunit, GGTase-I-alpha |
| 2 | B | Protein farnesyltransferase beta subunit | polymer | 401 | 44879.3 | 1 | UniProt (Q02293) Pfam (PF00432) In PDB | Rattus norvegicus (Norway rat) | CAAX farnesyltransferase beta subunit, RAS proteins prenyltransferase beta, FTase-beta |
| 3 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | B | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 5 | B | (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE | non-polymer | 473.0 | 1 | Chemie (736) | |||
| 6 | water | water | 18.0 | 388 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82570.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 920.8 | |
| All* | Total formula weight | 83491.4 |
