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2BDF

Src kinase in complex with inhibitor AP23451

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Proto-oncogene tyrosine-protein kinase Srcpolymer27931969.82UniProt (P12931)
Pfam (PF07714)
Homo sapiens (human)p60-Src, c-Src, pp60c-src
2C, D
(A, B)
{[(4-{[2-(4-AMINOCYCLOHEXYL)-9-ETHYL-9H-PURIN-6-YL]AMINO}PHENYL)(HYDROXY)PHOSPHORYL]METHYL}PHOSPHONIC ACIDnon-polymer494.42Chemie (24A)
3E, F
(A, B)
waterwater18.0502Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63939.5
Non-Polymers*Number of molecules2
Total formula weight988.8
All*Total formula weight64928.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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