2BBO
Human NBD1 with Phe508
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystic fibrosis transmembrane conductance regulator | polymer | 291 | 32500.9 | 1 | UniProt (P13569) Pfam (PF00005) | Homo sapiens (human) | CFTR, cAMP-dependent chloride channel |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D (A) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 389 - 678 (UniProt: P13569)
| PDB | External Database | Details |
|---|---|---|
| Ser 388 | - | cloning artifact |
| Leu 409 | Phe 409 | engineered mutation |
| Ser 429 | Phe 429 | engineered mutation |
| Leu 433 | Phe 433 | engineered mutation |
| Glu 550 | Gly 550 | engineered mutation |
| Gln 553 | Arg 553 | engineered mutation |
| Lys 555 | Arg 555 | engineered mutation |
| Arg 667 | His 667 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32500.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.5 | |
| All* | Total formula weight | 33032.4 |
