2BBA
Crystal Structure and Thermodynamic Characterization of the EphB4 Receptor in Complex with an ephrin-B2 Antagonist Peptide Reveals the Determinants for Receptor Specificity.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-B receptor 4 | polymer | 185 | 21088.0 | 1 | UniProt (P54760) Pfam (PF01404) | Homo sapiens (human) | Tyrosine-protein kinase receptor HTK |
| 2 | B (P) | Agonist peptide | polymer | 15 | 1707.9 | 1 | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F (A, P) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 17 - 196 (UniProt: P54760)
| PDB | External Database | Details |
|---|---|---|
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22795.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 22988.0 |
