2BAQ
p38alpha bound to Ro3201195
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 365 | 42087.0 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | MAP kinase p38 alpha |
| 2 | B (A) | [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE | non-polymer | 371.4 | 1 | Chemie (PQB) | |||
| 3 | C (A) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Ile 30 | Val 29 | engineered mutation |
| Css 162 | Cys 161 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42087.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 371.4 | |
| All* | Total formula weight | 42458.3 |
