2B92
Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interferon-induced guanylate-binding protein 1 | polymer | 328 | 37078.4 | 2 | UniProt (P32455) Pfam (PF02263) | Homo sapiens (human) | GTP-binding protein 1, Guanine nucleotide-binding protein 1, HuGBP-1 |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D, G (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | E, H (A, B) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 2 | Chemie (AF3) PubChem (2124) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 317 (UniProt: P32455)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | cloning artifact |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Met -3 | - | cloning artifact |
| Arg -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74156.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1103.0 | |
| All* | Total formula weight | 75259.9 |
