2B6B
Cryo EM structure of Dengue complexed with CRD of DC-SIGN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | envelope glycoprotein | polymer | 394 | 43819.4 | 3 | GenBank (323503) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (Q9WDA7) In PDB | Dengue virus | |
| 2 | D | CD209 antigen | polymer | 175 | 19920.0 | 1 | UniProt (Q96QQ4) Pfam (PF00059) UniProt (by SIFTS) (Q9NNX6) In PDB | Homo sapiens (human) | Dendritic cell-specific ICAM-3-grabbing nonintegrin 1, DC-SIGN1, DC-SIGN |
Sequence modifications
A, B, C: 1 - 394 (GenBank: 323503)
D: 251 - 404 (UniProt: Q96QQ4)
| PDB | External Database | Details |
|---|---|---|
| Glu 71 | Asp 71 | conflict |
| Asn 390 | Asp 390 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 230 | - | cloning artifact |
| Gly 231 | - | cloning artifact |
| Ser 232 | - | cloning artifact |
| Ser 233 | - | cloning artifact |
| His 234 | - | cloning artifact |
| His 235 | - | cloning artifact |
| His 236 | - | cloning artifact |
| His 237 | - | cloning artifact |
| His 238 | - | cloning artifact |
| His 239 | - | cloning artifact |
| Ser 240 | - | cloning artifact |
| Ser 241 | - | cloning artifact |
| Gly 242 | - | cloning artifact |
| Leu 243 | - | cloning artifact |
| Val 244 | - | cloning artifact |
| Pro 245 | - | cloning artifact |
| Arg 246 | - | cloning artifact |
| Gly 247 | - | cloning artifact |
| Ser 248 | - | cloning artifact |
| His 249 | - | cloning artifact |
| Met 250 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 151378.2 | |
| All* | Total formula weight | 151378.2 |
