2B43

Crystal structure of the Norwalk virus RNA dependent RNA polymerase from strain Hu/NLV/Dresden174/1997/GE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	non-structural polyprotein	polymer	526	58657.8	4	UniProt (Q6REV3) Pfam (PF00680)	Norovirus
2	E, F, G, H (A, B, C, D)	water	water		18.0	1122	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 510 (UniProt: Q6REV3)

PDB	External Database	Details
Met 0	-	cloning artifact
Thr 34	Ala 1223	SEE REMARK 999
Thr 107	Ala 1296	SEE REMARK 999
Gly 153	Glu 1342	SEE REMARK 999
Lys 236	Arg 1425	SEE REMARK 999
Ala 257	Ser 1446	SEE REMARK 999
Lys 291	Thr 1480	SEE REMARK 999
Lys 363	Arg 1552	SEE REMARK 999
Val 511	-	cloning artifact
Asp 512	-	cloning artifact
Lys 513	-	cloning artifact
Leu 514	-	cloning artifact
Ala 515	-	cloning artifact
Ala 516	-	cloning artifact
Ala 517	-	cloning artifact
Leu 518	-	cloning artifact
Glu 519	-	cloning artifact
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	234631.0
All*	Total formula weight	234631.0

*Water molecules are not included.