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2B3X

Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Iron-responsive element binding protein 1polymer88898374.41UniProt (P21399)
Pfam (PF00330)
Pfam (PF00694)
Homo sapiens (human)IRE-BP 1, Iron regulatory protein 1, IRP1, Ferritin repressor protein, Aconitate hydratase, Citrate hydro-lyase, Aconitase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
4D
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5E
(A)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight98374.4
Non-Polymers*Number of molecules3
Total formula weight479.1
All*Total formula weight98853.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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