2B0M
Human dihydroorotate dehydrogenase bound to a novel inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase, mitochondrial | polymer | 393 | 43009.9 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | Dihydroorotate oxidase; DHOdehase |
2 | A | 3-AMIDO-5-BIPHENYL-BENZOIC ACID | non-polymer | 317.3 | 1 | Chemie (201) | |||
3 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
4 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
5 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDB | External Database | Details |
---|---|---|
Met 4 | - | expression tag |
Gly 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
Ser 16 | - | expression tag |
Ser 17 | - | expression tag |
Gly 18 | - | expression tag |
His 19 | - | expression tag |
Ile 20 | - | expression tag |
Asp 21 | - | expression tag |
Asp 22 | - | expression tag |
Asp 23 | - | expression tag |
Asp 24 | - | expression tag |
Lys 25 | - | expression tag |
His 26 | - | expression tag |
Met 27 | - | expression tag |
Leu 28 | - | expression tag |
Glu 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 43009.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 929.8 | |
All* | Total formula weight | 43939.7 |