2AZN
X-RAY Structure of 2,5-diamino-6-ribosylamino-4(3h)-pyrimidinone 5-phosphate reductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Putative 5-amino-6-(5-phosphoribosylamino)uracil reductase | polymer | 219 | 24721.2 | 6 | UniProt (Q58085) Pfam (PF01872) | Methanocaldococcus jannaschii | HTP reductase |
| 2 | G, I, J, M, N... (A, B, C, D, F) | 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PY RAN-3,4,5-TRIOL | non-polymer | 452.5 | 8 | Chemie (MA5) | |||
| 3 | H, K, O, Q, R... (A, B, C, D, E...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 6 | Chemie (NAP) | |||
| 4 | L, V (B, F) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | AA, BA, W, X, Y... (E, F, A, B, C...) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 6 - 224 (UniProt: Q58085)
| PDB | External Database | Details |
|---|---|---|
| Mse 17 | Met 17 | modified residue |
| Mse 52 | Met 52 | modified residue |
| Mse 122 | Met 122 | modified residue |
| Mse 140 | Met 140 | modified residue |
| Mse 163 | Met 163 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 148327.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8557.0 | |
| All* | Total formula weight | 156884.0 |






