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2AZM

Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Mediator of DNA damage checkpoint protein 1polymer20722885.02UniProt (Q14676)
Pfam (PF16770)
Pfam (PF16589)
Homo sapiens (human)Nuclear factor with BRCT domains 1
2C, D
(C, D)
GAMMA-H2AX HISTONEpolymer101235.22UniProt (by SIFTS) (P16104)Histone H2AFX
3E, F, G, H
(A, B, C, D)
waterwater18.0351Chemie (HOH)
Sequence modifications
A, B: 1883 - 2089 (UniProt: Q14676)
PDBExternal DatabaseDetails
Mse 2014Met 2014modified residue
Mse 2029Met 2029modified residue
Mse 2086Met 2086modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight48240.4
All*Total formula weight48240.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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