2AZM
Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Mediator of DNA damage checkpoint protein 1 | polymer | 207 | 22885.0 | 2 | UniProt (Q14676) Pfam (PF16770) Pfam (PF16589) | Homo sapiens (human) | Nuclear factor with BRCT domains 1 |
2 | C, D (C, D) | GAMMA-H2AX HISTONE | polymer | 10 | 1235.2 | 2 | UniProt (by SIFTS) (P16104) | Histone H2AFX | |
3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B: 1883 - 2089 (UniProt: Q14676)
PDB | External Database | Details |
---|---|---|
Mse 2014 | Met 2014 | modified residue |
Mse 2029 | Met 2029 | modified residue |
Mse 2086 | Met 2086 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 48240.4 | |
All* | Total formula weight | 48240.4 |