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2AXN

Crystal structure of the human inducible form 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]polymer52059694.11UniProt (Q16875)
Pfam (PF01591)
Pfam (PF00300)
Homo sapiens (human)
2B
(A)
6-O-phosphono-beta-D-fructofuranosenon-polymer260.11Chemie (F6P)
3C
(A)
{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACIDnon-polymer292.21Chemie (EDT)
4D
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
5E
(A)
waterwater18.0353Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59694.1
Non-Polymers*Number of molecules3
Total formula weight979.6
All*Total formula weight60673.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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