2AWX

Synapse associated protein 97 PDZ2 domain variant C378S

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Synapse associated protein 97	polymer	105	11455.2	2	UniProt (Q62696) Pfam (PF00595)	Rattus norvegicus (Norway rat)	Presynaptic protein SAP97, SAP-97
2	C, D (B)	HISTIDINE	non-polymer		156.2	2	Chemie (HIS)
3	E, F (A, B)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A, B: 315 - 410 (UniProt: Q62696)

PDB	External Database	Details
Met 314	-	expression tag
Glu 315	Arg 314	SEE REMARK 999
Ile 317	Asn 316	SEE REMARK 999
Met 318	His 317	SEE REMARK 999
Ser 378	Cys 377	engineered mutation
Val 402	Ala 401	SEE REMARK 999
Ser 411	-	expression tag
Arg 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22910.4
Non-Polymers*	Number of molecules	2
	Total formula weight	312.3
All*	Total formula weight	23222.7

*Water molecules are not included.