2AW2
Crystal structure of the human BTLA-HVEM complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, X | B and T lymphocyte attenuator | polymer | 120 | 14101.8 | 2 | UniProt (Q7Z6A9) In PDB | Homo sapiens (human) | B and T lymphocyte-associated protein |
2 | B, Y | Tumor necrosis factor receptor superfamily member 14 | polymer | 108 | 11451.1 | 2 | UniProt (Q92956) Pfam (PF00020) In PDB | Homo sapiens (human) | Herpesvirus entry mediator A, Tumor necrosis factor receptor-like 2, TR2 |
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | D | beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G61843VN) | |||
5 | A | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
6 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, X: 26 - 137 (UniProt: Q7Z6A9)
B, Y: 1 - 104 (UniProt: Q92956)
PDB | External Database | Details |
---|---|---|
His 138 | - | expression tag |
His 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | cloning artifact |
Ser -2 | - | cloning artifact |
His -1 | - | cloning artifact |
Met 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 51105.8 | |
Branched | Number of molecules | 2 |
Total formula weight | 791.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 58.7 | |
All* | Total formula weight | 51956.3 |