2ANW
Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: Implications for structure-based design of protease inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | plasma kallikrein, light chain | polymer | 241 | 27099.8 | 1 | UniProt (P03952) Pfam (PF00089) | Homo sapiens (human) | Kininogenin; Fletcher factor |
| 2 | B (A) | BENZAMIDINE | non-polymer | 120.2 | 1 | Chemie (BEN) | |||
| 3 | C (A) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 16 - 248 (UniProt: P03952)
| PDB | External Database | Details |
|---|---|---|
| Ser 122 | Cys 503 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27099.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 120.2 | |
| All* | Total formula weight | 27220.0 |
