2ANJ
Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor 2 | polymer | 263 | 29244.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2 |
| 2 | B (A) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 1 | Chemie (KAI) PubChem (3816) PubChem (10255) PubChem (73345) PubChem (23616889) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6453379) PubChem (6604705) PubChem (10036135) PubChem (11095940) PubChem (6603893) PubChem (101994997) PubChem (135037246) | |||
| 3 | C (A) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P19491)
A: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| Trp 61 | Tyr 471 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | SEE REMARK 999 |
| Thr 119 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29244.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 213.2 | |
| All* | Total formula weight | 29458.0 |
