2AMP
Crystal Structure Of Porcine Transmissible Gastroenteritis Virus Mpro in Complex with an Inhibitor N1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase | polymer | 304 | 33267.5 | 2 | UniProt (Q9IW06) Pfam (PF05409) UniProt (by SIFTS) (P0C6Y5) | Transmissible gastroenteritis virus | tgev main protease, 3CL-PRO |
| 2 | C, D (A, B) | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | non-polymer | 618.7 | 2 | Chemie (I12) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 302 (UniProt: Q9IW06)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66535.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1237.4 | |
| All* | Total formula weight | 67772.5 |
